Monday, September 6th, 2010

Medical devices offer alternatives in the treatment for Congestive Heart Failure.

Congestive heart unfortunate (CHF) is a condition where the heart is not functioning properly due to the weakening of the heart muscle. As cardiac muscle is damaged, it looses it ability to squeeze strongly and causing a decreased output of blood flow and perfusion to the body and organs. Factors that lead to CHF are [...]

Effective Antibodies who Developed them and when were they launched?

Antibody

Indication

Developer

Launch

Reopro

Coronary restenosis

Centocor

1995

Rituxan

NHL

IDEC

1997

Remicade

RA and Crohn’s

Centocor

1998

Synagis

RSV

MedImmune

1998

Herceptin

Breast Cancer

Genentech

1998

Facts about Protein Based Drugs

Examples of Classes of Protein-based Biotech drugs
Erythropoietin (EPO)
Blood factors
Growth Factors: Becaplermin
Human Growth Hormone: HGH, Somatotropin, Sermorelin
Cytokines
i) Interleukins (ILs): Interleukin-11 (rhIL-11, oprelvekin,
Neumega)
ii) Interferons
iii) Colony-Stimulating Factors (CSF)
Enzymes: Adenosine deaminase, photolyase
Issues related to the use of accelerator based drugs
1) Antigenicity
2) Stability
3) Drug Delivery
What is the challenge with Protein Based Drugs?
Developing drugs to treat human disease; accelerator based drugs [...]

Summary of Breakdown of Biotechnology Sectors

The following is a summary of Biotechnology Sectors. It is intended as an
overview of relevant areas, rather than a complete listing of biotechnology research and
development. In alphabetical order.
Ag-Bio
• Plant biotechnology (e.g. tissue culture, embryogenesis, genetic markers, genetic engineering, plant
breeding, floriculture, forestry)
• Animal biotechnology (e.g. diagnostics, therapeutics, embryo transplantation, genetic markers,
genetic engineering, animal breeding, anti-microbials)
• Biofertilisers, [...]