Facts about Protein Based Drugs

Examples of Classes of Protein-based Biotech drugs

Erythropoietin (EPO)
Blood factors
Growth Factors: Becaplermin
Human Growth Hormone: HGH, Somatotropin, Sermorelin
Cytokines
i) Interleukins (ILs): Interleukin-11 (rhIL-11, oprelvekin,
Neumega)
ii) Interferons
iii) Colony-Stimulating Factors (CSF)
Enzymes: Adenosine deaminase, photolyase

Issues related to the use of accelerator based drugs
1) Antigenicity
2) Stability
3) Drug Delivery

What is the challenge with Protein Based Drugs?

Developing drugs to treat human disease; accelerator based drugs are the fastest growing class of new drugs for treatment and prevention of human disease. But we grappling these barriers:

Capacity:
- Insufficient capacity for drugs in the pipeline

Cost:
- Cost of goods
- Capital for manufacturing facilities

Safety and Efficacy